{VERSION 5 0 "IBM INTEL NT" "5.0" } {USTYLETAB {CSTYLE "Maple Input" -1 0 "Courier" 0 1 255 0 0 1 0 1 0 0 1 0 0 0 0 1 }{PSTYLE "Normal" -1 0 1 {CSTYLE "" -1 -1 "Times" 1 12 0 0 0 1 2 2 2 2 2 2 1 1 1 1 }1 1 0 0 0 0 1 0 1 0 2 2 0 1 }{PSTYLE "Title " -1 18 1 {CSTYLE "" -1 -1 "Times" 1 18 0 0 0 1 2 1 1 2 2 2 1 1 1 1 } 3 1 0 0 12 12 1 0 1 0 2 2 19 1 }{PSTYLE "Author" -1 19 1 {CSTYLE "" -1 -1 "Times" 1 12 0 0 0 1 2 2 2 2 2 2 1 1 1 1 }3 1 0 0 8 8 1 0 1 0 2 2 0 1 }} {SECT 0 {EXCHG {PARA 18 "" 0 "" {TEXT -1 10 "AIDS Model" }}{PARA 19 " " 0 "" {TEXT -1 15 "file: aids.mws" }}}{EXCHG {PARA 0 "" 0 "" {TEXT -1 111 "The model is based on the work in Anderson and May, and report ed in Murray. Extensions are based on the papers" }}{PARA 0 "" 0 "" {TEXT -1 44 "by Castillo-Chavez, Cooke, Huang, and Levin." }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 36 "restart; with(DEtools): with(plots) :" }}}{EXCHG {PARA 0 "" 0 "" {TEXT -1 114 "Variables: S=susceptibles, In=infectives (HIV positive), A=full blown AIDS, Z=HIV positive not i nfectious did not" }}{PARA 0 "" 0 "" {TEXT -1 12 "develop AIDS" }} {PARA 0 "" 0 "" {TEXT -1 0 "" }}{PARA 0 "" 0 "" {TEXT -1 110 "Paramete rs: B=immigration rate into susceptibles, mu= natural death rate, l ambda= probabilitiy of acquiring" }}{PARA 0 "" 0 "" {TEXT -1 119 "infe ction from a randomly chosen partner = beta*In/N where beta=transmissi on probability, c= number of sexual partners," }}{PARA 0 "" 0 "" {TEXT -1 66 "d=AIDS death rate, v= rate of conversion from HIV positiv e to AIDS" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 29 "N(t) := S(t)+I n(t)+A(t)+Z(t);" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 175 "odes := diff(S(t),t)= B - mu*S(t) -beta*In(t)*S(t)/N(t),diff(In(t),t)=beta*In (t)*S(t)/N(t)-(v+mu)*In(t), diff(A(t),t)=p*v*In(t)-(d+mu)*A(t),diff(Z( t),t)=(1-p)*v*In(t)-mu*Z(t);" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 45 "ICs := A(0)=0, Z(0)=0, S(0)=99900, In(0)=100;" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 70 "B:= 13333.3; v:=0.2; mu := 1.0/32; d:= 1. 0; p:=0.3; beta:=5.15*v;c:=1;" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 82 "soln:=dsolve(\{odes,ICs\},\{S(t),In(t),Z(t),A(t)\},type=numeric, output=listprocedure);" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 81 "s := subs(soln,S(t)); i:=subs(soln,In(t));a:=subs(soln,A(t)); z:=subs(s oln,Z(t));" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 26 "plot(\{i(t),a (t)\},t=0..20);" }}}{EXCHG {PARA 0 "> " 0 "" {MPLTEXT 1 0 0 "" }}}} {MARK "12" 0 }{VIEWOPTS 1 1 0 1 1 1803 1 1 1 1 }{PAGENUMBERS 0 1 2 33 1 1 }